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吩噻嗪类药物是精神病患者的常用药物,并因其止吐、抗组织胺和镇痛作用而在临床广泛使用。本文叙述该类药物的心血管作用。电生理和心电图变化:动物实验显示,吩噻嗪类对离体心房肌、心室肌和浦顷野纤维均有作用。它通过减慢动作电位0位相最大上升速率而使膜反应
Phenothiazines are commonly used drugs for people with mental disorders and are widely used clinically for antiemetic, antihistamine and analgesic effects. This article describes the cardiovascular effects of these drugs. Electrophysiological and electrocardiographic changes: Animal experiments show that phenothiazines have a role in isolated atrial myocardium, ventricular muscle and Pu are wild fibers. It causes the membrane to react by slowing down the maximum rate of rise of the action potential 0 phase