目的 :进一步认识喉淀粉样变性病的发病机制、分类、临床表现、诊断及治疗。方法 :11例喉淀粉样变性病患者 ,行间接喉镜下手术 5例 ,支撑喉镜下手术 1例 ,喉裂开术 2例 ,垂直半喉切除声门重建术 1例 ,未手术 2例。结果 :3例失访 ,2例复发 ,6例情况稳定。结论 :①Symmers分类方法具有临床价值 ;②诊断、鉴别诊断依据刚果红染色呈棕红色 ,偏光显微镜下呈双折光和绿荧光的特殊形态 ;③喉淀粉样变性确诊后 ,必须排除全身性、继发性淀粉样变性及多发性浆细胞瘤 ;④治疗依赖患者的严重程度 ,轻者可以保守观察 ,重者必须外科切除 ;⑤可以复发 ,必须长期随访。 Objective: To further understand the pathogenesis, classification, clinical manifestation, diagnosis and treatment of laryngeal amyloidosis. Methods: Eleven patients with laryngeal amyloidosis underwent indirect laryngoscope operation in 5 cases, laryngoscope support in 1 case, laryngeal rupture in 2 cases, vertical half-laryngectomy in 1 case, and no operation in 2 cases . Results: Three patients were lost to follow-up and two patients relapsed. Six patients were stable. Conclusion: ①Symmers classification has clinical value; ②Diagnosis, differential diagnosis based on Congo red staining was reddish brown, polarized light microscope under the special form of birefringence and green fluorescence; ③ laryngeal amyloidosis diagnosis, you must rule out systemic, secondary Amyloidosis and multiple plasmacytoma; The treatment depends on the severity of the patient, the light can be observed conservatively, severe cases must be surgically removed; ⑤ can relapse, we must long-term follow-up.