应用单克隆抗体分离主要的淋巴细胞亚群NK、CD_+~4、CD_8~+、B细胞,分别测定其对K_(562)瘤细胞的杀伤活性及各亚群细胞的协同作用。本实验结果表明,除NK细胞外,CD_4~+、CD_8~+、B细胞均能单独杀伤肿瘤细胞,各亚群的对比无显著差异。淋巴细胞中除某一亚群的混合细胞杀伤力大于该亚群本身,并提示T细胞系统在肿瘤免疫中的重要作用。 Monoclonal antibodies were used to isolate the main lymphocyte subsets NK, CD_+~4, CD_8~+, and B cells, and the killing activity against K562 tumor cells and the synergistic effect of the cells in each subgroup were measured. The results of this experiment showed that except for NK cells, CD4+, CD8+, and B cells could kill tumor cells alone, and there was no significant difference in the subgroups. The killing power of mixed cells except for one subgroup of lymphocytes is greater than that of the subpopulation itself, and it suggests that the T cell system plays an important role in tumor immunity.