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宿主的免疫反应在持续性HBV感染中起关键作用[1] 。最近有人用HBsAg及其相关蛋白治疗慢性HBV感染 ,取得了一定的疗效[2 ] 。提示HBsAg有可能作为治疗慢性持续性HBV感染的药物之一。1 材料和方法1.1 材料 HBV转基因BALB/c小鼠 ,由全军传染病中心自行研制并培育。正常BALB/c小
Host immune response plays a key role in persistent HBV infection [1]. Recently, some people with HBsAg and its related proteins in the treatment of chronic HBV infection, and achieved a certain effect [2]. Tip HBsAg may be used as one of the drugs for the treatment of chronic persistent HBV infection. 1 Materials and Methods 1.1 Materials HBV transgenic BALB / c mice, developed and cultivated by the All-China Infectious Diseases Center. Normal BALB / c small