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目的探讨急性一氧化碳中毒时血糖升高的机制,以及血糖升高对临床主要症状、生化指标的相关性影响。方法选取107例急性一氧化碳中毒患者,先按病情分为轻、中、重三度,分析不同程度中毒者空腹血糖变化的趋势;再根据空腹血糖情况分为血糖正常组及升高组,分析血糖升高与昏迷程度、心肌酶谱变化之间可能存在的关系。结果血糖升高者的中毒程度、昏迷程度、心肌酶谱变化程度与血糖正常者相比有显著性差异。结论急性一氧化碳中毒时血糖随中毒程度加深而升高加剧,并且血糖升高的程度与昏迷程度、心肌酶谱变化程度呈正相关。
Objective To investigate the mechanism of hyperglycemia in acute carbon monoxide poisoning and the effect of hyperglycemia on the main clinical symptoms and biochemical indexes. Methods A total of 107 patients with acute carbon monoxide poisoning were enrolled. The patients were divided into light, medium and heavy according to their condition. The trend of fasting blood glucose in different degree of poisoning was analyzed. According to the fasting blood glucose, the patients were divided into normal blood glucose group and elevated blood glucose group. Elevated and coma, myocardial enzyme changes may exist between the relationship. Results hyperglycemia poisoning, coma, changes in myocardial enzymes and blood glucose levels were significantly different. Conclusion The blood glucose in acute carbon monoxide poisoning aggravates with the degree of poisoning and increases exacerbatedly, and the degree of hyperglycemia is positively correlated with the degree of coma and the changes of myocardial enzymes.