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1999年 5月至 1999年 8月 ,我科使用硫酸依替米星治疗肺癌合并支气管阻塞性肺炎 2 0例 ,取得很好疗效。硫酸依替米星 (杭州爱大制药公司生产 ,商品名 :爱大 ) 2 0 0 mg加入 5 %葡萄糖 2 5 0 ml,每日 1次静脉滴注 ,体外放疗加速器治疗肺癌 ,每日 2 0 0 c Gg,疗程 7～ 10 d。结果 ,2 0例中治愈 15例 ,显效 2例 ,进步 2例 ,无效 1例。治愈 +显效 17例 ,占 85 %。用药后 3d内退热者 12例 ,47d退热者 8例 ,随热退症状体征好转。用药后白细胞 3d内降到正常者 9例 ,7d内降到正常者 7例。治疗前分离出铜绿假单胞菌 4株 ,肺炎克雷伯氏菌5株 ,大肠埃希氏菌、产气杆菌、金葡球菌各 2株 ,表葡球菌、肠球菌、链球菌各 1株。治疗后 ,除铜绿假单胞菌、肺炎克雷伯氏菌、金葡球菌各 1株未清除外 ,其余均得到清除 ,总清除率 83.3% ,值得在呼吸道疾病中推广。
From May 1999 to August 1999, 20 cases of lung cancer complicated with bronchial obstructive pneumonia were treated with etimicin sulfate in our department, and achieved good results. Etimicin sulfate (produced by Hangzhou Aida Pharmaceutical Co., Ltd., trade name: Ai Da) 200 mg 5% dextrose 250 ml once daily intravenous infusion, in vitro radiotherapy accelerator for lung cancer 20 0 c Gg, treatment 7 ~ 10 d. Results, 20 cases were cured in 15 cases, 2 cases markedly improved in 2 cases, 1 case was ineffective. Cure + effective in 17 cases, accounting for 85%. 12 cases of fever in 3d after treatment, fever in 47d in 8 cases, with signs of heat withdrawal symptoms improved. After treatment, leukocytes decreased to normal in 3 cases in 9 cases, 7 days reduced to normal in 7 cases. Four strains of Pseudomonas aeruginosa, five strains of Klebsiella pneumoniae, two strains of Escherichia coli, Aerobacter aerogenes and Staphylococcus aureus, one strain of Staphylococcus epidermidis, one of Enterococcus and Streptococcus were isolated before treatment. . After treatment, in addition to Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus were not cleared, the rest were removed, the total clearance rate of 83.3%, worth promoting in respiratory diseases.