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硼酸乙醇溶液对治疗中耳炎、外耳道炎等效果良好,因其配制过程简单,局部用药方便,在五官科应用较为广泛。但由于该制剂在冬季室温低于15℃时,易析出结晶,影响疗效,为此,我们对配制方法作一些改进,并观察其在不同温度下含量变动情况. 一、配方根据硼酸易溶于甘油的特点,我们在该制剂中加入不同量的甘油,配制成Ⅱ、Ⅲ号溶液,并与未加甘油的Ⅰ号溶液比较,见表1。
Ethanol solution of boric acid for the treatment of otitis media, otitis media and other effects of good, because of its preparation process is simple, convenient local administration, ENT more widely used. However, due to the preparation in the winter when the room temperature is below 15 ℃, easy to precipitate crystals, affecting the curative effect, for which we make some improvements to the preparation method, and observe the changes in the content under different temperatures. The characteristics of glycerol, we added different amounts of glycerol in the preparation, formulated as Ⅱ, Ⅲ solution, and without glycerol Ⅰ solution comparison, shown in Table 1.