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目的:分析对社区老年原发高血压合并糖尿病患者采用氨氯地平、缬沙坦联合治疗的临床疗效。方法:对近一年来我院门诊收治的126例社区老年原发性高血压合并T2DM患者患者进行观察,随机分为联合组和对照组。对照组单独采用氨氯地平治疗,联合组采用氨氯地平、缬沙坦联合治疗,治疗3个月,观察两组血压、血糖变化情况。结果:联经过3个月的治疗后,两组患者的血糖、血压水平均有所下降,联合组血糖各项指标、血压水平明显低于对照组,对比差异有统计学意义(P<0.05)。结论:对社区老年原发性高血压合并T2DM患者采用氨氯地平、缬沙坦联合治疗的疗效明显,可以平稳的达到降压、降糖治疗目的,长期使用的不良反应少。用药方便,老年患者的耐受性好,值得推广。
OBJECTIVE: To analyze the clinical efficacy of amlodipine and valsartan in elderly patients with hypertension in the community with diabetes mellitus. Methods: A total of 126 community-aged patients with primary hypertension complicated with T2DM admitted to our hospital in the past year were observed and randomly divided into the combined group and the control group. The control group was treated with amlodipine alone. The combination group was treated with amlodipine and valsartan for 3 months. The changes of blood pressure and blood glucose were observed. Results: After three months’ treatment, the blood glucose and blood pressure decreased in both groups. The indexes of blood glucose and blood pressure in the combined group were significantly lower than those in the control group (P <0.05) . Conclusion: The combination therapy of amlodipine and valsartan is superior to the elderly patients with T2DM in senile essential hypertension. The combination therapy of valsartan is effective, and the antihypertensive and hypoglycemic effects can be smoothly achieved. There are few adverse reactions in long-term use. Convenient medication, elderly patients are well tolerated, it is worth promoting.