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胃癌的发生、发展和转移与机体的免疫功能密切相关。胃癌局部组织内的免疫反应与全身免疫功能的变化并不一致。研究机体对胃癌的免疫作用,了解癌组织的局部免疫反应十分重要。Inberg 对575例胃癌进行病理分析,发现弥漫型胃癌局部免疫细胞浸润少,5年存活率低;肠型胃癌局部免疫细胞浸润明显,5年存活率高。国内也有类似报导。児玉好史、陈铁镇等对胃癌局部淋巴结进行研究,亦发现T 淋巴细胞区(PH)和B 淋巴细胞区(GH)增生明显者5年存活率明显升高。说明胃癌组织内的T、B 淋巴细胞均能抑制肿瘤生
The occurrence, development and metastasis of gastric cancer are closely related to the body’s immune function. The immune response in local tissues of gastric cancer is not consistent with the changes in systemic immune function. It is very important to study the immune effect of the body on gastric cancer and understand the local immune response of cancer tissue. Inberg’s pathological analysis of 575 cases of gastric cancer found that diffuse gastric cancer had less local immune cell infiltration and a low 5-year survival rate. Intestinal type gastric cancer had significant immunological cell infiltration and a high 5-year survival rate. There are similar reports in China. The research on the regional lymph nodes in gastric cancer by Sashiro Hayashi and Chen Tiezhen also found that the five-year survival rate of T lymphocyte area (PH) and B lymphocyte area (GH) hyperplasia was significantly increased. It shows that T and B lymphocytes in gastric cancer can inhibit tumor growth