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目的采用美罗华联合 CHOP 方案和单用 CHOP 方案两种方法治疗初治的弥漫性大 B 细胞淋巴瘤,以比较两种方法的疗效及不良反应。方法用同期对照的前瞻性研究方法,将72例弥漫性大 B 细胞淋巴瘤患者分为联合治疗组和 CHOP 组。联合组34例采用CHOP 方案加美罗华(375mg/m~2,于每周期化疗前2天静脉滴注1次)治疗。CHOP
Objective To treat the newly diagnosed diffuse large B cell lymphoma with rituximab combined CHOP regimen and single CHOP regimen in order to compare the curative effects and adverse reactions of the two methods. Methods 72 patients with diffuse large B-cell lymphoma were divided into combined treatment group and CHOP group by prospective study with the same period. Thirty-four patients in the combined group were treated with CHOP regimen plus rituximab (375 mg / m ~ 2, intravenously 1 day prior to each cycle of chemotherapy). CHOP