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目的了解济南市男男性行为人群梅毒感染状况,为制定防治措施提供依据。方法 2009-2012年每年4-6月份,采用滚雪球抽样方法对男男性行为人群进行问卷调查并采集血液检测梅毒抗体。结果 2009-2012年共调查男男性行为人群1 588人,梅毒阳性率分别是6.2%、6.0%、9.5%和15.0%(χ2=25.29,P<0.01);2012年梅毒阳性率与2009年和2010年分别比较,有显著性升高。分层分析结果显示,21~30岁年龄组男男性行为人群梅毒感染率上升较快,由2009年的4.5%上升到2012年的14.5%,差异有统计学意义(χ2=18.76,P<0.01)。梅毒感染与有关因素分析显示,40岁以上年龄组(OR=4.211,P<0.01)、初中及以下文化程度者(OR=2.387,P<0.01)感染梅毒风险较大。结论济南市男男性行为人群是梅毒感染高危人群,应重点加大21~30岁年龄组干预力度,控制梅毒的传播。
Objective To understand the status of syphilis infection among men who have sex with men (MSM) in Ji’nan City, and to provide basis for the prevention and control measures. Methods From April to June every year from 2009 to 2012, a sample of snowballs was used to conduct a questionnaire survey on men who had sex with men and collected blood to detect syphilis antibody. Results A total of 1 588 MSM were surveyed between 2009 and 2012 and the positive rates of syphilis were 6.2%, 6.0%, 9.5% and 15.0% respectively (χ2 = 25.29, P <0.01) 2010 respectively, a significant increase. Stratified analysis showed that syphilis infection rates among men and women in 21-30 age group increased rapidly from 4.5% in 2009 to 14.5% in 2012, with significant difference (χ2 = 18.76, P <0.01) ). Syphilis infection and related factors analysis showed that the risk of syphilis infection was higher in those over 40 years of age (OR = 4.211, P <0.01), those with junior high school education and below (OR = 2.387, P <0.01). Conclusions The population of MSM in Ji’nan is a high risk population of syphilis infection. The intervention in 21 ~ 30 years old group should be emphasized to control the spread of syphilis.