目的探讨腹水超滤浓缩回输治疗肝硬化顽固性腹水的临床疗效。方法对48例肝硬化顽固性腹水患者采用腹水超滤浓缩回输腹腔治疗。结果治疗后患者腹胀减轻,尿量、血浆白蛋白显著增加,血浆尿素氮和肌酐水平下降,腹腔积液减少或消失。结论自体腹水超滤浓缩回输是治疗肝硬化顽固性腹水的安全、有效方法。 Objective To investigate the clinical effect of ascites ultrafiltration concentrated reinfusion treatment of refractory cirrhosis and ascites. Methods Forty-eight patients with cirrhosis and refractory ascites were treated with ultrafiltration of ascites and transfusion in the abdominal cavity. Results After treatment, patients with bloating reduced, urine output, plasma albumin increased significantly, plasma urea nitrogen and creatinine levels decreased, ascites decreased or disappeared. Conclusion Ascites ultrafiltration concentrated reinfusion is a safe and effective treatment of refractory cirrhosis and ascites.