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目的观察急性脑卒中时脱水剂甘露醇与甘油果糖注射液交替应用的临床疗效。方法选择252例急性脑卒中患者,按组别单用甘露醇和甘露醇与甘油果糖注射液交替应用,观察各组临床疗效和引起的心、肾功能损害。结果两组对临床疗效的影响无显著差异,对心、肾功能损害有显著差异。结论甘露醇与甘油果糖注射液交替应用,在不影响临床疗效的前提下能有效地减少单用甘露醇的不良反应。
Objective To observe the clinical effect of alternating application of dehydration agent mannitol and glycerol fructose injection in acute stroke. Methods A total of 252 patients with acute stroke were enrolled in this study. Mannitol, mannitol and glycerol fructose alone were used alternately to observe the clinical effects and cardiac and renal dysfunction in each group. Results There was no significant difference between the two groups in the clinical efficacy, and significant differences in cardiac and renal dysfunction. Conclusion Mannitol and glycerol fructose injection alternately, without affecting the clinical efficacy of premise can effectively reduce the adverse reactions of mannitol alone.