许多研究证明吸入二氧化硅粉尘会引起肺泡巨噬细胞的大量增殖和崩解,而尘细胞崩解是纤维化的最初环节。已有实验证实,尘细胞的增殖和崩解与粉尘毒性强弱、吸入量多少及纤维化程度呈一致关系。因此,估价吞噬硅尘的尘细胞在肺内蓄积 Many studies have shown that inhalation of silica dust causes a large number of alveolar macrophages proliferation and disintegration, and the collapse of dust cells is the first part of fibrosis. Experiments have confirmed that the proliferation and disintegration of dust cells and the dust toxicity, the amount of inhalation and the degree of fibrosis was consistent. Therefore, it is estimated that dust cells that engulfed the silica dust accumulate in the lungs