青光眼视神经萎缩之发生机理,有血管理论及神经压迫学说等观点。1972年Maumenee对血管理论提出不同看法,认为可能与轴浆运输有关,但有争议。我们用辣根过氧化物酶(HRP)逆行追踪技术来研究实验性高眼压对白兔视神经逆行轴浆运输的影响,以为青光眼视力障碍之病理机制提供实验资料。现将第一轮实验结果予以简报。 The mechanism of glaucomatous optic atrophy, vascular theory and neural oppression theory point of view. In 1972, Maumenee put forward different opinions on the theory of blood vessels, which may be related to the axoplasmic transport, but it is controversial. We use horseradish peroxidase (HRP) retrograde tracing technique to study the effect of experimental ocular hypertension on retrograde axonal transport of optic nerve in white rabbits to provide experimental data for the pathogenesis of glaucomatous vision disorders. Now the first round of experimental results to be briefed.