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米非司酮具有孕激素受体(PR)和糖皮质激素受体拮抗剂的作用。近年来米非司酮抗肿瘤作用受到重视。研究表明其在子宫平滑肌瘤治疗中是很有前途的药物之一。现就米非司酮治疗子宫平滑肌瘤的临床应用及其机理加以综述。
Mifepristone has a progestin receptor (PR) and glucocorticoid receptor antagonist effect. In recent years, anti-tumor effect of mifepristone attention. Studies have shown that it is one of the promising drugs in the treatment of uterine leiomyomas. Now on the clinical application of mifepristone treatment of uterine leiomyoma and its mechanism are reviewed.