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目的探讨高血糖时红细胞（ＲＢＣ）聚集在急性脑梗塞（ＣＩ）发病中的作用。方法８７例急性ＣＩ患者依有无糖尿病（ＤＭ）及空腹血糖水平分组检测血液流变学指标。结果ＤＭ组ＥＥＴ显著延长，与高血糖反应组均有ＥＳＲ及其方程Ｋ值显著增高；正常血糖组以全血低切粘度、聚集指数增高为著。结论高血糖时ＣＩ患者红细胞聚集增强，糖尿病伴发ＣＩ患者尤著。ＲＢＣ聚集性增强可能是ＤＭ伴发腔隙性梗塞的原因之一，对高血糖时ＣＩ面积增大及脑水肿的加重有影响。
Objective To investigate the role of erythrocyte (RBC) aggregation in the pathogenesis of acute cerebral infarction (CI) during hyperglycemia. Methods Eighty-seven acute CI patients were divided into two groups according to their diabetes mellitus (DM) and fasting blood glucose (FBG) to detect hemorrheological parameters. Results EET was significantly prolonged in DM group, and both ESR and K value in hyperglycemia group were significantly higher than those in hyperglycemia group. In normal blood glucose group, whole blood low shear viscosity and aggregation index were increased. Conclusion High blood sugar in CI patients with enhanced erythrocyte aggregation, especially in patients with diabetes and CI. RBC aggregation may be one of the causes of DM with lacunar infarction, which has an impact on the increase of CI area and the increase of cerebral edema in hyperglycemia.