乙型肝炎是全球性重要疾病,全世界有3亿以上HBV携带者,它是80%原发性肝癌的原因,在HBV携带率达到或超过10%的国家,HBV感染引起的死亡可能占全部死亡中的3%。在全世界50亿人口中,35亿生活在HBV中度或高度(HBV慢性带毒率超过2%)流行区,慢性带毒者中75%以上在亚洲。在HBV低流行区,感染主要在成年期发生,通过性 Hepatitis B is a globally important disease with more than 300 million HBV carriers worldwide and is responsible for 80% of primary liver cancers. In countries with HBV carrier rates of 10% or more, deaths due to HBV infection may account for all 3% of deaths. Of the 5 billion people worldwide, 3.5 billion live in moderate or high HBV (more than 2% of chronic HBV carriers) and more than 75% of chronic carriers are in Asia. In areas of low HBV prevalence, infection occurs predominantly in adulthood, through sex