作者报告20例随访10～25年的头颈部神经纤维瘤情况。20例中女12,男8,初诊年龄1～45岁,平均21.5岁。11例有多发性神经纤维瘤(Von Recklinghausen病)的家族史。17例诊断为多发性神经纤维瘤,均可见咖啡牛乳色斑,其中8例呈多发性。神经纤维瘤生长的部位包括;头皮10,颊10,颈6,额5,眼睑4,眼眶4,上颌骨3,下颌骨3,腮腺3,腭3, The authors reported 20 cases of head and neck neurofibromas that were followed up for 10 to 25 years. Among the 20 cases, 12 were females and 8 were males. The initial diagnosis age was 1 to 45 years old with an average of 21.5 years old. Eleven patients had a family history of multiple neurofibromatosis (Von Recklinghausen disease). 17 cases were diagnosed with multiple neurofibromas, and all of them showed milky macules, of which 8 cases were multiple. The sites of growth of neurofibroma include: scalp 10, buccal 10, neck 6, forehead 5, eyelid 4, eyelid 4, maxilla 3, mandible 3, parotid gland 3, fistula 3,