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１引言异丙嗪为组胺Ｈ１受体拮抗剂，其分子结构中含一个手性中心，即存在对映异构体。β－环糊精（β－ＣＤ）与大多数药物分子形成包络物，使药物分子水溶性增加和药效延长。本文研究了异丙嗪与β-ＣＤ形成包络物的紫外光谱性质，比较了异丙嗪和异丙嗪－β-ＣＤ包络物最大吸?
1 Introduction Promethazine is a histamine H1 receptor antagonist with a chiral center in its molecular structure, ie the presence of enantiomers. Beta-cyclodextrin (β-CD) forms an envelope with most drug molecules, increasing the water-solubility and prolongation of the drug’s molecule. In this paper, the UV spectra of promethazine and β-CD were studied. The maximal absorption of promethazine and promethazine-β-CD envelop was compared.