近年来高龄生育比例世界范围内逐年增长,我国因2016年“二孩”政策全面开放,高龄夫妇助孕比例呈爆发式增长。然而,高龄妇女助孕风险高、成功率低,孕期并发症、合并症高,围产儿发病率和死亡率高,出生缺陷发生率高。因此,目前高龄助孕安全性凸显。 In recent years, the proportion of advanced births has been increasing year by year in the world. Because of the full liberalization of the “two children” policy in 2016, the proportion of elderly couples living in pregnancy shows an explosive growth. However, older women have a higher risk of pregnancy, lower success rates, higher complications during pregnancy, higher comorbidities, higher perinatal morbidity and mortality, and higher rates of birth defects. Therefore, the current safety of older pregnant prominence highlights.