自抗癌药物问世以来,人们便向往利用体外试验的方法来选择肿瘤敏感之药物。迄今已建立了不少特殊的测试系统,其中大多数的判断指标皆用诸如细胞形态学的改变、细胞成活力改变、细胞代谢抑制、放射性前体物参入的变化等.最近,人们又喜用肿瘤细胞生殖能力的改变作为检测抗癌药物效应的指标,认 Since the advent of anti-cancer drugs, people have longed for in vitro tests to select tumor-sensitive drugs. Up to now, a number of special test systems have been set up, and most of them use changes such as changes in cell morphology, changes in cell viability, inhibition of cell metabolism, changes in radioactive precursors, etc. Changes in the reproductive capacity of tumor cells as an indicator of the effect of anticancer drugs