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目的观察左卡尼汀联合促红素治疗肾性贫血的疗效。方法将肾性贫血患者30例随机分成两组,治疗组于每次血液透析后静脉注射左卡尼汀及促红素,而对照组仅注射促红素,疗程16周。结果治疗组血红蛋白、红细胞压积升高明显优于对照组,治疗组高血压、低血压、肌肉痉挛发生率均低于对照组。结论左卡尼汀能显著提高促红素治疗尿毒症肾性贫血的疗效,减少EPO用量,降低促红素的不良反应发生率,提高患者的生存质量。
Objective To observe the efficacy of levocarnitine and erythropoietin in treating renal anemia. Methods Thirty patients with renal anemia were randomly divided into two groups. The treatment group received intravenous levocarnitine and erythropoietin after each hemodialysis, while the control group received only erythropoietin for 16 weeks. Results The hemoglobin and hematocrit in the treatment group were significantly higher than those in the control group. The incidences of hypertension, hypotension and muscle spasm in the treatment group were lower than those in the control group. Conclusion L-carnitine can significantly improve the efficacy of erythropoietin in treatment of uremic renal anemia, reduce the dosage of EPO, reduce the incidence of adverse reactions of erythropoiesis and improve the quality of life of patients.