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迄今已有不少实验室证明肿瘤细胞附着性(adh-esiveness)与转移能力有关。人们推测认为,在转移过程中循环于外周血的肿瘤细胞对于血管或淋巴管表面的附着能力是形成转移灶的重要环节,而不少因素又可影响肿瘤细胞的这种附着作用。本文报道前列腺素对于肿瘤细胞附着性的影响。实验用悬浮培养的Walker256瘤细胞,培养液为含10%胎牛血清的RPMI-1640。观察指标为本细胞在前列腺素作用下对于尼龙纤维及塑料培养碟表面
To date, many laboratories have demonstrated that the adh-es- siveness of tumor cells is related to the ability to metastasize. It has been speculated that in the process of metastasis, tumor cells that circulate in the peripheral blood to the surface of blood vessels or lymphatic vessels are an important part of the formation of metastases, and many factors can affect the attachment of tumor cells. This article reports the effect of prostaglandins on the adhesion of tumor cells. The suspension was cultured in Walker256 tumor cells in a RPMI-1640 medium containing 10% fetal bovine serum. Observe that the cells are under the action of prostaglandins on nylon fiber and plastic culture dish surface