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早期诊断肺癌用紫外线辅助纤维支气管内窥镜术和细胞学检查法。由于费用昂贵和系创伤性诊断法,难于用作大规模筛选。因此须寻求其他的早期检测方法。应用特殊的呼气收集技术及电子计算机辅助气相色谱/质谱法(GC/MC),已证明肺癌病人呼气中丙酮、甲基乙基酮及正丙醇等若干挥发性有机化合物含量高。用12个肺癌病人的样品和17个正常人对照样品的 GC/MC 描绘图谱经电子计算机统计,发现具有显著
Early diagnosis of lung cancer with UV-assisted fiberoptic bronchoscopy and cytology. It is difficult to use as a large-scale screening because it is expensive and traumatic. Therefore, other early detection methods must be sought. Using special breath collection techniques and computer-aided gas chromatography/mass spectrometry (GC/MC), it has been demonstrated that lung cancer patients have high levels of volatile organic compounds such as acetone, methyl ethyl ketone, and n-propanol. The GC/MC profile of 12 lung cancer patient samples and 17 normal human control samples was statistically calculated by computer and found to be significant.