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本实验以大鼠为实验对象，用去氧胆酸钠诱发急性胰腺炎，观察了急性胰腺炎时胰腺的组织学变化及茵陈蒿汤的影响。结果显示：大鼠于诱发急性胰腺炎早期，胰腺组织出现严重的出血、坏死及大量的炎细胞浸润，胰腺细胞的线粒体肿胀，嵴消失，初级溶酶体增多，内质网排列不整齐，囊泡状扩张，脱颗粒，酶原颗粒少而小。用茵陈蒿汤治疗后其组织学观察胰腺病变很轻，表明茵陈蒿汤对胰腺本身的结构具有保护作用。
In this experiment, rats were used as the experimental object, with sodium deoxycholate induced acute pancreatitis, observed the histological changes of pancreas in acute pancreatitis and Yinchenhao decoction. The results showed that in the early stage of acute pancreatitis in rats, there were severe hemorrhage, necrosis and inflammatory cell infiltration in the pancreas. The mitochondria of pancreatic cells swollen, the ridges disappeared, the primary lysosomes increased, the endoplasmic reticulum was irregularly arranged, Bubble expansion, degranulation, small and small particles of zymogen. Histological observation with Yin Chen Hao decoction treatment of pancreatic lesions is very light, indicating that Yin Chen Hao decoction on the structure of the pancreas itself has a protective effect.