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为探讨华蟾素注射液治疗慢性乙型肝炎疗效及其对细胞免疫功能的影响。将５９例慢性乙型肝炎分为保肝药物基础上加用华蟾素注射液治疗３２例（治疗组）；保肝药物治疗２７例（对照组）。结果显示：治疗组比对照组具有显著降低血清丙氨酸转氨酶；提高ＨＢｅＡｇ的阴转率、抗ＨＢｅ阳转率，ＨＢ－ＶＤＮＡ阴转率；增加外周血Ｔ淋巴细胞亚群中ＣＤ＋３、ＣＤ＋４细胞，降低ＣＤ＋８细胞作用。表明华蟾素注射液治疗慢性乙型肝炎是通过提高机体细胞免疫功能而发挥抗病毒和减轻对肝细胞的破坏
To investigate the therapeutic effect of cinobufacini injection on chronic hepatitis B and its effect on cellular immune function. Fifty-nine patients with chronic hepatitis B were divided into hepatoprotective drugs and 32 cases treated with cinobufacini injection (treatment group), while 27 cases were treated with hepatoprotective drugs (control group). The results showed that the treatment group had significantly lower serum alanine aminotransferase than the control group; increased the negative conversion rate of HBeAg, anti-HBe positive conversion rate, HB-VDNA negative conversion rate; increased peripheral blood T lymphocyte subsets CD +3, CD +4 cells , Reduce the role of CD +8 cells. The results showed that cinobufacini injection in the treatment of chronic hepatitis B exerted anti-virus and reduced damage to hepatocytes by enhancing cellular immunity