论文部分内容阅读
采用型特异性引物ＰＣＲ分型法对５０例肝细胞癌组织中感染的丙型肝炎病毒（ＨＣＶ）进行基因分型。结果显示：单独ＨＣＶⅡ型感染为６０％（３０／５０）；单独Ⅲ型感染６％（３／５０）；感染为Ⅱ＋Ⅲ型１０％（５／５０），Ⅱ＋Ⅳ型为１６％（８／５０），Ⅱ＋Ⅰ＋Ⅲ型为４％（２／５０）；Ⅰ～Ⅳ型均阴性的病例４％（２／５０）。表明湖南地区肝细胞癌患者的ＨＣＶ感染以Ⅱ型为主，并存在Ⅱ型与其它型的混合感染；少数病例可能系单独Ⅲ型感染所致
Type-specific primer PCR was used to genotype 50 cases of hepatocellular carcinoma (HCV) infected hepatitis C virus (HCV). The results showed that: HCV type II infection alone was 60% (30/50); type III infection alone was 6% (3/50); infection was type II+III 10% (5/50), type II+IV was 16% (8/50) Type II+I+III was 4% (2/50); I-IV type was negative in 4% (2/50). It was shown that HCV infection in patients with hepatocellular carcinoma in Hunan is dominated by type II, and there is mixed infection of type II and other types; a small number of cases may be caused by a single type III infection.