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目的调查和分析广西初治肺结核病患者使用抗结核药间歇疗法中治疗情况,以提出相应的处理措施。方法对2004年4月～2005年10月在广西4所结核病专科医院和2所大型综合医院住院的初治肺结核病患者781例治疗情况,以及抗结核药物各种不良反应率进行回顾性调查。结果初治肺结核病患者中断治疗率为14.47%,不良反应发生率为15.75%,因不良反应为所有中断治疗原因的首位,占中断治疗构成的37.17%。结论不良反应是广西肺结核病患者中断治疗的主要原因,应引起相关部门重视,采取相应的措施确保抗结核治疗方案顺利完成。
Objective To investigate and analyze the treatment of patients with tuberculosis in newly diagnosed tuberculosis patients in Guangxi using intermittent therapy of antituberculosis drugs to put forward the corresponding treatment measures. Methods A retrospective survey was conducted on 781 newly diagnosed tuberculosis patients hospitalized in 4 TB hospitals and 2 large general hospitals in Guangxi from April 2004 to October 2005 and various adverse reactions of anti-tuberculosis drugs. Results The rate of discontinuation of treatment was 14.47% and the rate of adverse reactions was 15.75%. The adverse reaction was the first cause of all the interruptions and accounted for 37.17% of the total. Conclusions Adverse reactions are the main reasons for the interruption of treatment for TB patients in Guangxi and should be taken seriously by the relevant departments. Corresponding measures should be taken to ensure the successful completion of the anti-TB treatment plan.