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胶原性疾病(简称胶原病)多可产生消化系统病变的症状,但也可由治疗药物所引起,其鉴别比较困难。本文就各种胶原性疾病引起的消化系统病变、发病机制及与药物的关系作一探讨。胶原病引起的消化系统病变慢性风湿性关节炎(RA) 在本病中发生率最高的是消化性溃疡。不少报道认为其发病与非类固醇抗炎剂和类固醇等治疗药物有关。女性居多,以胃底部较难治愈的单发性或多发性溃疡为特征,H-受体阻滞剂治疗无效。内镜检查发现用非类固醇后发生溃疡的有28.6％,
Collagen disease (referred to as collagen disease) can produce symptoms of digestive system lesions, but also caused by the treatment of drugs, the identification of more difficult. In this paper, a variety of collagen diseases caused by digestive diseases, pathogenesis and the relationship between drugs for a discussion. Digestive System Lesions Due to Collagen Disease Chronic Rheumatoid Arthritis (RA) The highest incidence of peptic ulcer disease in this disease. Many reports that the incidence of non-steroidal anti-inflammatory drugs and steroids and other therapeutic drugs. Mostly female, more difficult to cure at the bottom of the stomach is characterized by solitary or multiple ulcers, H-receptor blockers ineffective treatment. Endoscopy found that non-steroidal ulcers occurred after 28.6%