皮质类固醇类药物的免疫抑制效果已为普遍认知,而它对于免疫系统机制的影响尚缺乏认识。不过,有几份调查报道可的松水平和细胞因子产生的相关性。在本项研究中作者检测了人脐血中可的松的含量。脐血样品采自正常孕期阴道分娩健康婴儿而血样品采自健康成人供血者,分别进行分析。作者的资料显示,脐血中可的松水平显著增加。相反采自剖腹产术产出婴儿的样本的可的松水平似乎是正常的。为研究可的松对于α干扰素(IFN-α)产生的影响作了进一步的实验。从健康成人志 The immunosuppressive effect of corticosteroids has become generally recognized, and its impact on the immune system mechanisms remains poorly understood. However, several studies have reported the association between cortisone levels and cytokine production. The authors examined the content of cortisone in human umbilical cord blood in this study. Umbilical cord blood samples taken from normal pregnant vaginal delivery of healthy infants and blood samples taken from healthy adult blood donors were analyzed. The author’s data show that cord blood cortisol levels increased significantly. On the contrary, the cortisone level taken from a coffin-producing baby’s sample appeared to be normal. To further investigate the effect of cortisone on the production of interferon alpha (IFN-α). From healthy adults Chi