目的　探讨组合药液湿化给氧对呼吸衰竭的疗效。方法　对 12 8例同期入院的呼吸衰竭患者 ,随机抽样分组施行两种氧疗方法。观察组 6 4例 ,在湿化液中加入消炎、解痉、化痰、平喘药物给氧 ,并与对照组 6 4例传统蒸馏水湿化给氧法对比并作相关分析。结果　观察组总有效率为 96 87% ,对照组总有效率为 82 81% ,经卡方检验 ,P <0 0 1,两组间有显著差异。结论　组合药液湿化给氧方法简便 ,是治疗呼吸衰竭的一项有效措施。 Objective To investigate the curative effect of combined liquid wet oxygenation on respiratory failure. Methods One hundred and twenty-eight patients with respiratory failure who were hospitalized in the same period were randomly divided into two groups. Sixty-four patients in the observation group were given anti-inflammatory, antispasmodic, phlegm-resolving and antiasthmatic drugs in the wetting solution. The results were compared with those in the control group of 64 cases of traditional distilled water wetting and oxygenating method. Results The total effective rate was 96 87% in observation group and 82 81% in control group. There was significant difference between the two groups by Chi-square test (P <0.01). Conclusion The combination of liquid wet oxygen therapy method is simple, is an effective measure for the treatment of respiratory failure.