报道了安乃近的单扫描示波极谱法测定。样品在酸性条件下用碘将其氧化 ,然后在 p H=1 1 .0的氨 -氯化铵缓冲液中 ,起扫电位 -0 .4 0 V ( vs.SCE )测定 -0 .76V处的二次导数峰高。峰高与安乃近浓度在 0 .0 1～ 3 μg/m L范围内呈线性关系。检出限为 0 .0 0 5μg/m L。同时对该氧化产物的极谱行为和反应机理作了探讨。方法用于测定安乃近的含量 ,结果满意。 A single scanning oscillopolarographic determination of metamizole was reported. The sample is oxidized with iodine under acidic conditions and then is swept at -0.04 V (vs.SCE) in ammonia-ammonium chloride buffer at pH = 1 1.0 The second derivative peak height. The peak height and the concentration of metamizumab in the range of 0. 0 1 ~ 3 μg / m L showed a linear relationship. The detection limit was 0.050μg / m L. At the same time, the polarographic behavior and reaction mechanism of the oxidation product were discussed. The method was used to determine the content of metamizole and the results were satisfactory.