论文部分内容阅读
人类的肿瘤有时是由于具有恶性潜能的基因移位所致。至少有4个实验室独自进行的最新研究表明。某些小鼠和人类的肿瘤(包括伯基特淋巴瘤)均与某基因myc从一个染色体移位至另一个染色体有关(《Science News》1982:319页)。目前在纽约的斯隆—凯特林纪念肿瘤中心的研究工作还涉及发生同样移位的第二种基因。 William Hayward等已对mos基因予以定位,是与myc基因同在人类8号染色体的臂上,但是mos的距离稍远一些。他们观察到,在患急性淋巴细胞白血病病人的8号染色体上
Human tumors are sometimes caused by translocation of genes with malignant potential. The latest research conducted by at least four laboratories shows that. Certain mouse and human tumors (including Burkitt’s lymphoma) are related to the translocation of a gene myc from one chromosome to another (Science News, 1982: 319). The current research work at the Sloan-Kettering Memorial Cancer Center in New York City also involves the second gene that has undergone the same shift. William Hayward et al. have mapped the mos gene to be on the human chromosome 8 arm with the myc gene, but the distance to mos is a bit farther. They observed that on chromosome 8 of patients with acute lymphoblastic leukemia