对伦敦两个医院1961～1988年喉部分切除术118例进行了回顾性分析,其中80例早期喉癌经全剂量放疗失败后行补救性手术治疗。放疗平均剂量为65Gy。补救性手术包括垂直部分喉切除术60例,水平部分喉切除术20例。12例15侧同时行根治性颈清扫。放疗后部分切除最严重的问题是易产生并发症,如进食困难,肺部感染,拔管困难,喉狭窄,伤口崩裂与瘘管等导致延迟愈合。少数患者需长期戴管或需胃造瘘解决营养问题。分析85年以前71例放疗后行部分喉切除术病人,垂直部分喉切除组54例,术后存活3年以上者36例(66.6%)局部复发9例,颈转移3例,死于癌者6例,死于其他疾病8例。水平部分喉切除组17例,存活3年以上者6例(35.3%),局部复发3例,颈转 A retrospective analysis of 118 cases of partial laryngectomy at two London hospitals from 1961 to 1988 was performed. Eighty cases of early laryngeal cancer were treated with salvage surgery after failure of full-dose radiation therapy. The average dose of radiotherapy was 65 Gy. Remedial surgery included vertical partial laryngectomy in 60 patients and horizontal partial laryngectomy in 20 patients. Twenty-nine patients underwent radical neck dissection at the same time. The most serious problem with partial resection after radiotherapy is susceptibility to complications such as eating difficulties, lung infections, difficulty in extubation, laryngeal stricture, wound rupture, and fistulas leading to delayed healing. A small number of patients need to wear a tube for a long period of time or need to have stomach fistula to solve the nutritional problem. Analysis of 71 patients who underwent partial laryngectomy after radiotherapy in 85 years and 54 patients in the vertical partial laryngectomy group. 36 patients (66.6%) who had postoperative survival for more than 3 years had local recurrence in 9 patients, and neck metastases in 3 patients who died of cancer. In 6 cases, 8 cases died of other diseases. Horizontal partial laryngectomy group (17 cases), surviving 3 years (6 cases (35.3%)), local recurrence (3 cases), cervical rotation