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目的：观察侧入法神经干脉冲射频治疗三叉神经痛的临床疗效及安全性。方法22例原发性三叉神经二、三支痛患者，根据解剖定位行侧入法神经干脉冲射频治疗。治疗前后进行VAS评分，观察术后临床疗效、不良反应。结果21例患者穿刺成功，1例穿刺失败。治疗1次14例，治疗2次4例，治疗3次3例。脉冲射频术后全部患者疼痛缓解，术后1d、3d、1wVAS评分分别为（3.26±1.13），（2.05±0.95），（1.28±0.59），较治疗前均有显著降低（<0.01）；优良率分别为66.6豫、71.4豫、80.9豫。无严重不良反应发生。术后1年随访18例，优良率61.1豫；5例复发，占27.7豫。结论侧入法神经干脉冲射频治疗原发性三叉神经痛是一种简便、有一定疗效、安全的治疗方法。“,”Objective To observe the clinical efficacy and safety of pulsed radio-frequence on nerve cord through lateral approach in patients with primary trigeminal neuralgia (PTN). Methods Twenty-two patients of PTN were treated with pulsed radio-frequence on nerve cord through lateral approach.The VAS scores,clinical efficacy and complication were observed after treatment.Results Twenty one patients were punctured successfully.One was punctured in failure.14 patients were treated one time,4 patients 2 times,3 patients 3 times. After treatment. All patients have pain relief.the VAS were 3.26±1.13,2.05±0.95,1.28±0.59 1 day,3 days and 1 week after treatment respectively,decreased compared with that before treatment ( <0.01).and the satisfactory rate were 66.6%,71.4%,80.9%respectively.no serious complication occurred in all of the patients.18 patients were involved in the follow up survey 1 year after treatment,and the satisfactory rate were 61.1%, 5 patients reoccurred,the recurrence rate was 27.7%. Conclusion Pulsed radio-frequence on nerve cord through lateral approach is a simple and effective and safe treatment for the patients of primary trigeminal neuralgia.