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目的探讨香烟烟雾对雄性大鼠性激素(睾酮、促卵泡生成激素、促黄体生成激素)的影响。方法雄性大鼠30只,按体重随机分为吸烟组、戒烟组、正常对照组。采用放免法对各组雄性大鼠进行睾酮(T)、促卵泡生成激素(FSH)、促黄体生成激素(LH)的水平进行测定。数据采用SPSS 17.0软件进行统计分析。结果吸烟组T、FSH、LH水平均低于正常对照组,且有统计学意义(P<0.05);戒烟组T、FSH、LH水平均低于正常对照组,无统计学意义(P>0.05)。结论被动吸烟后雄性大鼠血清性激素水平均下降。
Objective To investigate the effects of cigarette smoke on sex hormones (testosterone, follicle stimulating hormone, luteinizing hormone) in male rats. Methods Thirty male rats were randomly divided into smoking group, smoking cessation group and normal control group according to body weight. The levels of testosterone (T), follicle stimulating hormone (FSH) and luteinizing hormone (LH) in male rats in each group were determined by radioimmunoassay. Data using SPSS 17.0 software for statistical analysis. Results The levels of T, FSH and LH in smoking group were lower than those in normal control group (P <0.05). The levels of T, FSH and LH in smoking cessation group were lower than those in normal control group (P> 0.05 ). Conclusions After passive smoking, the levels of serum sex hormones in male rats decreased.