胰岛β细胞功能缺陷和胰岛素抵抗是2型糖尿病发生发展机制中的两个重要环节。因此,糖尿病的治疗不仅要改善胰岛素抵抗,还要阻止β细胞功能的衰竭。1.2型糖尿病胰岛β细胞功能的异常β细胞功能缺陷表现在胰岛素分泌的质和量的变化以及分泌形式的异常等多方面。至少可从以下几方 Islet β-cell dysfunction and insulin resistance are two important mechanisms in the development of type 2 diabetes mellitus. Therefore, the treatment of diabetes not only to improve insulin resistance, but also to prevent the failure of β-cell function. Abnormal beta-cell dysfunction in type 1 diabetes The beta-cell dysfunction manifests itself in many aspects, such as changes in the amount and quantity of insulin secreted, and abnormalities in the secretory form. At least from the following parties