桔梗为在消炎、排脓药,镇咳、祛痰药的汉方方剂中配伍的生药,已有关于其主要成分platycodin类的镇咳、祛痰等各种生理作用的报告。其中platycodin D为重要的质量标准成分。但尚未见有关介绍对该成分进行直接定量的精确度高的方法的报告。因此,以在质量评价中广泛应用为目的,研究了生药及汉方提取物制剂中的HPLC定量法。 The Platycodon grandiflora is a crude drug that is compatible with anti-inflammatory, antipyretic, antitussive, and anti-tuberculosis prescriptions. It has reported on various physiological effects of its main component, platycodin, such as antitussive and expectorant. Among them, platycodin D is an important quality standard component. However, no report has been published on a highly accurate method for the direct quantification of this component. Therefore, for the purpose of extensive application in quality evaluation, HPLC quantification methods for crude drug and Chinese herbal extract preparation were studied.