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对一硝基苯甲酰还原青蒿素(代号79019)为上海医工院合成的又一种青蒿素衍生物。一、急性毒性试验:79019对小鼠口服与肌肉注射的急性LD(50)分别为:1307.12mg/kg(95％可信限为1159.9-1446.3mg/kg);177.5mg/kg(158.5-192.6mg/kg);
The mononitrobenzoyl reduction of artemisinin (code 79019) is another artemisinin derivative synthesized by Shanghai Medical Engineering Institute. First, the acute toxicity test: 79019 oral and intramuscular injection of acute LD (50) were: 1307.12mg / kg (95% confidence limit 1159.9-1446.3mg / kg); 177.5mg / kg (158.5-192.6 mg / kg);