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心脏病患者用利尿剂治疗时预防缺钾是很重要的。众所周知,缺钾使心肌对毛地黄敏感。而利尿剂对体内钾的影响如何,由于研究的方法不同结果不一致。临床上是否需要补钾意见仍有分歧。作者用Baron和Ahmed法,从肝素化的血液中测定白细胞的钾、钠和水含量。研究了18例慢性心脏瓣膜病而无水肿患者(心脏病组),10例不是心脏病而由于其他原因用利尿剂者(非心脏病组)和59例正常人(对照组)白细胞钾、钠和水的变化。二组病人用利尿磺胺、噻嗪类和保钾的利尿剂联合治疗,同时补钾历时6周至14年。心脏病组全部都使用了地高辛。
It is important to prevent potassium deficiency in patients with heart disease when treated with diuretics. It is well known that potassium deficiency causes the myocardium to be sensitive to foxglove. And diuretics on the body of potassium how, due to the method of research different results inconsistent. Whether the need for clinical potassium supplement is still divided. The authors used Baron and Ahmed’s method to determine the potassium, sodium and water content of leukocytes from heparinized blood. 18 patients with chronic heart valve disease without edema (heart disease group), 10 patients without heart disease and other reasons with diuretics (non-heart disease group) and 59 normal people (control group) And water changes. Two groups of patients with diuretic sulfonamide, thiazide and potassium-saving diuretic combination therapy, while potassium for 6 weeks to 14 years. All of the cardiomes used digoxin.