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目的观察克拉霉素治疗慢性鼻—鼻窦炎(CRS)的临床效果。方法选取医院接收治疗的CRS患者44例,给予克拉霉素缓释片治疗,比较患者治疗前后的VAS评分和Lund-Mackey鼻窦CT评分。结果 44例患者治疗后VAS评分和Lund-Mackey鼻窦CT评分均明显低于治疗前,差异均有统计学意义(P<0.05)。44例患者临床检查中发现有23例患者属于双侧鼻窦炎,另外21例是单侧,确定本次试验所有患者鼻窦炎共67侧,治疗后67侧Lund-Mackey评分优于治疗前,差异有统计学意义(P<0.05)。结论克拉霉素治疗CRS疗效较好,具有重要临床意义。
Objective To observe the clinical effect of clarithromycin on chronic rhinosinusitis (CRS). Methods Forty-four patients with CRS admitted to hospital were treated with clarithromycin sustained-release tablets. The VAS score and Lund-Mackey CT score were compared before and after treatment. Results The VAS score and Lund-Mackey CT score of 44 patients after treatment were significantly lower than those before treatment, the difference was statistically significant (P <0.05). In the 44 patients, 23 patients were found to have bilateral sinusitis in the clinical examination. The other 21 patients were unilateral. All 67 patients with sinusitis were determined in this trial. The 67 Lund-Mackey scores were better than those before treatment There was statistical significance (P <0.05). Conclusion Clarithromycin treatment of CRS better effect, has important clinical significance.