Laron型侏儒症是少见的常染色体隐性遗传性生长障碍疾病,1966年由Laron等所报道。本症特点是患儿身材特别矮小,有严重垂体性侏儒的表型,但生长激素(GH)水平升高,生长介素(IGF-Ⅰ)显著降低,用hGH治疗无效。本症似多见于亚洲中东地区,但无严格的种族区分,亦无性别差异。国内尚未见诸文献,现将本院所见一例报道于下。 Laron dwarfism is a rare disease of autosomal recessive growth disorder, reported by Laron et al in 1966. This disease is characterized by a particularly short stature in children with severe pituitary dwarf phenotype, but elevated levels of growth hormone (GH), growth hormone (IGF-Ⅰ) was significantly reduced, with hGH treatment ineffective. This disease is more common in the Middle East, Asia, but no strict racial discrimination, nor gender differences. The country has not seen the literature, the hospital now see a case report below.