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目的:观察泌尿生殖道感染患者解脲支原体、人型支原体感染情况及对抗生素的敏感性。方法:泌尿、生殖道感染者405例行支原体培养和10种抗生素的药物敏感试验。结果:支原体培养阳性率49.38%(200/405),其中解脲支原体阳性率37.53%(152/405)、人型支原体阳性率2.72%(11/405)、解脲支原体+人型支原体合并感染阳性率9.14%(37/405);男性培养阳性率28.73%(25/87),女性培养阳性率55.03%(175/318),二者比较差异有统计学意义(χ2=18.9,P<0.01);耐药率交沙霉素3.5%、强力霉素4.5%、美满霉素5.5%,壮观霉素9.5%、司帕霉素12.9%、克拉霉素21.5%、阿奇霉素21.5%、罗红霉素43.0%、环丙沙星53.5%、氧氟沙星79.0%。结论:解脲支原体是常见泌尿生殖道感染病原菌,对各种抗生素产生耐药性,应根据药物敏感试验结果合理选用敏感抗生素。
Objective: To observe the infection of Ureaplasma urealyticum and Mycoplasma hominis and the sensitivity to antibiotics in patients with genitourinary tract infection. Methods: 405 cases of urinary and reproductive tract infections were treated with mycoplasma and 10 kinds of antibiotics drug sensitivity test. Results: The positive rate of mycoplasma culture was 49.38% (200/405), of which the positive rate of Ureaplasma urealyticum was 37.53% (152/405), the positive rate of Mycoplasma hominis was 2.72% (11/405), the combination of Ureaplasma urealyticum and Mycoplasma hominis The positive rate was 9.14% (37/405). The positive rate was 28.73% (25/87) in male and 55.03% (175/318) in female. The difference was statistically significant (χ2 = 18.9, P <0.01) ); Resistance rate of josamycin 3.5%, doxycycline 4.5%, minocycline 5.5%, spectinomycin 9.5%, 12.9% of the sparamicin, clarithromycin 21.5% azithromycin 21.5% 43.0% prime, 53.5% ciprofloxacin, and ofloxacin 79.0%. Conclusion: Ureaplasma urealyticum is a common pathogen of genitourinary tract infection, a variety of antibiotic resistance, should be based on the results of drug susceptibility testing rational use of sensitive antibiotics.