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目的探讨安静时１２３Ｉβ甲基碘苯脂十五烷酸（ＢＭＩＰＰ）心肌断层显像（简称１２３ＩＢＭＩＰＰＳＰＥＣＴ）对劳力性心绞痛的诊断价值，并与运动负荷２０１Ｔｌ心肌断层显像（简称２０１ＴｌＳＰＥＣＴ）对比分析。方法对３２例劳力性心绞痛患者及１２例健康对照者进行１２３ＩＢＭＩＰＰＳＰＥＣＴ及２０１ＴｌＳＰＥＣＴ检查；将左室划分为９个节段，采用４级评分法对各节段放射性分布进行半定量评价（ＤＳ）。结果心绞痛组２０１ＴｌＳＰＥＣＴ表现为放射性分布低下的节段大于１２３ＩＢＭＩＰＰＳＰＥＣＴ，二者ＤＳ的一致率为６０８％。１２３ＩＢＭＩＰＰＳＰＥＣＴ检出冠状动脉狭窄病变的敏感性、特异性及准确性分别为６２％、９２％、７０％，２０１ＴｌＳＰＥＣＴ为８４％、８３％、８４％，１２３ＩＢＭＩＰＰＳＰＥＣＴ的敏感性明显低于２０１ＴｌＳＰＥＣＴ（Ｐ＜００５）。冠状动脉狭窄支数越多，病变程度越重，１２３ＩＢＭＩＰＰＳＰＥＣＴ的检出率越高。结论安静时１２３ＩＢＭＩＰＰＳＰＥＣＴ对劳力性心绞痛冠状动脉狭窄的检出及其程度的判定有一定的临床价值。
Objective To investigate the diagnostic value of 123Iβmethyliodobenzenepentadecanoic acid (BMIPP) myocardial perfusion imaging (123IBMIPPSPECT) in patients with exercise-induced angina at rest, and to evaluate the value of 201Tl SPECT )Comparative analysis. Methods Thirty-two patients with angina pectoris and 12 healthy controls were examined with 123IBMIPPSPECT and 201TSPECT. The left ventricle was divided into nine segments and the four-point scoring method was used to semi-quantitatively evaluate the radioactivity distribution of each segment (DS) . Results 201TlSPECT angina group showed low radioactive segments greater than 123I MBIPPSPECT, the consistency of the two DS was 60 8%. The sensitivity, specificity and accuracy of 123IBMIPPSPECT for detection of coronary artery stenosis were 62%, 92%, 70%, and 201TlSPECT were 84%, 83%, 84%, respectively. The sensitivity of 123IBMIPPSPECT was significantly lower than that of 201TSPECT (P <005). The more the number of coronary stenosis, the more severe lesions, the higher the detection rate of 123I MBIPPSPECT. Conclusions 123I MBIPPSPECT at rest in the diagnosis of coronary heart disease with angina pectoris and determination of the degree of certain clinical value.