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目的:探讨阿仑膦酸钠、钙尔奇D治疗糖尿病伴骨质疏松症的临床疗效,总结其临床应用价值。方法:选取72例糖尿病伴骨质疏松症的患者,随机分为观察组和对照组,每组36例,观察组使用阿仑膦酸钠、钙尔奇D治疗,对照组单纯使用钙尔奇D治疗,观察比较两组治疗效果。结果:观察组显效18例,有效16例,无效2例,总有效率为94.4%;对照组显效16例,有效14例,无效6例,总有效率为83.3%,两组疗效比较差异显著(P<0.05);通过视觉模拟评分(VAS)进行疼痛评分,两组治疗前后的疼痛程度比较存在明显差异(P<0.05),观察组改善程度更为显著(P<0.05)。结论:阿仑膦酸钠、钙尔奇D治疗糖尿病伴骨质疏松症的临床疗效显著,优于单独使用钙尔奇D治疗,能够明显改善临床症状,减轻疼痛,值得临床推广使用。
Objective: To investigate the clinical efficacy of alendronate sodium and calcium chloride D in the treatment of diabetic patients with osteoporosis, and to summarize its clinical value. Methods: Seventy-two patients with diabetes mellitus and osteoporosis were randomly divided into observation group and control group, with 36 cases in each group. The observation group was treated with alendronate sodium and calcium chloride D, while the control group was treated with calcium alone D treatment, observed and compared the treatment effect of two groups. Results: In the observation group, 18 cases were markedly effective, 16 cases were effective and 2 cases were ineffective. The total effective rate was 94.4%. In the control group, 16 cases were markedly effective, 14 cases were effective and 6 cases were ineffective. The total effective rate was 83.3%. There was significant difference between the two groups (P <0.05). The visual analogue scale (VAS) was used to evaluate the pain scores before and after treatment. There was significant difference between the two groups before and after treatment (P <0.05). The improvement degree of the observation group was more significant (P <0.05). Conclusion: The clinical efficacy of alendronate sodium and calcitriod D in the treatment of diabetic patients with osteoporosis is significantly better than that of treatment with calcitriol alone, which can significantly improve the clinical symptoms and relieve the pain and is worthy of clinical promotion.