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慢性粒细胞性白血病（CML）是一种起源于骨髓多能造血于细胞的恶性增殖性疾病。CML一旦进入加速期和急变期常规治疗效果不理想。高三尖杉酯碱（HHT）是治疗急性白血病国产药物。国外有报道用于治疗晚期慢性期慢粒病人。我院用小剂量HHT联合DA方案治疗8例CML加速急变期患者，有?
Chronic myeloid leukemia (CML) is a malignant proliferative disease that originates in the bone marrow pluripotent hematopoietic cells. Once CML enters the accelerated period and the rapid transformation period, the conventional treatment is not ideal. Homoharringtonine (HHT) is a domestic drug used to treat acute leukemia. It has been reported abroad for the treatment of patients with advanced chronic granulocytosis. Our hospital used low dose HHT combined with DA regimen to treat 8 patients with CML accelerated blast crisis.