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目的:探讨超敏C反应蛋白(hs-CRP)在2型糖尿病(T2DM)并发心血管病变患者中血清水平变化。方法:将86例T2DM患者依据病情分为心血管病变组(46例)及单纯T2DM组(40例),以40名健康自愿者作为对照组,检测3组血清hs-CRP水平。结果:T2DM并发心血管病变组患者血清hs-CRP水平为(5.14±2.78)mg/L,单纯T2DM组为(3.26±1.35)mg/L,均高于对照组(1.29±0.88)mg/L,均P<0.05。结论:hs-CRP水平与T2DM患者并发心血管病变密切相关,可以通过hs-CRP的动态监测作为预测T2DM并发心血管病变危险性的重要实验室指标。
Objective: To investigate the changes of serum hs-CRP levels in patients with type 2 diabetes mellitus (T2DM) complicated with cardiovascular diseases. Methods: Eighty-six patients with T2DM were divided into two groups according to the disease: cardiovascular disease group (46 cases) and simple T2DM group (40 cases). Forty healthy volunteers were used as control group to detect serum hs-CRP levels in three groups. Results: The serum levels of hs-CRP in patients with T2DM complicated with cardiovascular disease were (5.14 ± 2.78) mg / L and (3.26 ± 1.35) mg / L in T2DM group, respectively, which were significantly higher than those in control group (1.29 ± 0.88) mg / L , All P <0.05. CONCLUSION: The level of hs-CRP is closely related to cardiovascular disease in patients with T2DM. The dynamic monitoring of hs-CRP can be used as an important laboratory index to predict the risk of T2DM complicated with cardiovascular disease.