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目的探讨米索前列醇直肠给药与口服给药治疗产后出血的效果。方法选取商丘市睢阳区妇幼保健院2013年4月至2015年5月产科收治的顺产产妇60例作为研究对象,将其随机分为对照组与观察组,各30例。给予对照组产妇口服米索前列醇,观察组产妇采取直肠给药米索前列醇。比较两组产妇产后出血量及不良反应发生率。结果治疗后观察组产妇的产时、产后2 h及产后24 h出血量均少于对照组,不良发应发生率低于对照组,差异均有统计学意义(P<0.05)。结论采用米索前列醇直肠给药治疗产妇产后出血效果优于口服给药,可明显降低产妇产妇出血量,值得临床推广使用。
Objective To investigate the effect of misoprostol rectal administration and oral administration on postpartum hemorrhage. Methods Sixty cases of primiparous obstetrics and gynecology admitted to the Maternal and Child Health Hospital of Xingyang District in Shangqiu City from April 2013 to May 2015 were selected and randomly divided into control group and observation group, with 30 cases in each group. The control group was given oral misoprostol and the observation group was given rectal misoprostol. The incidence of postpartum hemorrhage and adverse reactions in the two groups were compared. Results After treatment, the amount of bleeding in the observation group was less than that in the control group at 2 h postpartum and 24 h postpartum. The incidence of adverse reactions was lower in the observation group than in the control group (P <0.05). Conclusion The rectal administration of misoprostol is superior to oral administration in the treatment of postpartum hemorrhage, which can significantly reduce the amount of maternal bleeding and deserve clinical promotion.