急性中毒是指有毒物质通过皮肤黏膜、呼吸道、消化道等途径进入人体内,造成靶器官损伤,其特点是起病急、病情重,如果不能及时有效救治严重者会很快危及生命,目前对急性中毒患者的治疗方法主要为洗胃、导泻、应用特效解毒剂等常规治疗和对患者进行血液净化治疗。1955年Schreiner首次报道了用血液透析治疗1例急性中毒患者,此后的近60年,血液滤过、血液透析、血液灌流、血液置换和血浆置换等血液净化疗法相继出现,血液净 Acute poisoning refers to the toxic substances through the skin and mucous membranes, respiratory tract, digestive tract and other means into the human body, resulting in target organ damage, which is characterized by acute onset, severe illness, if not timely and effective treatment of severe cases will soon be life-threatening, the current The treatment of acute poisoning patients mainly gastric lavage, cathartic, antidote and other special effects and other conventional treatment of patients with blood purification treatment. Schreiner first reported in 1955 hemodialysis treatment of 1 case of acute poisoning patients, the next 60 years, hemofiltration, hemodialysis, hemoperfusion, blood replacement and plasma exchange and other blood purification therapy have emerged, the net blood